TIPTOP SOURCE INDEX

Public science beginning with tiptop original ingredient identities

Start with tiptop’s INCI identities in the United States and JCIA identities in Japan then explore the FDA ODD record public clinical studies and peer-reviewed research behind the wider scientific landscape

INCI and JCIA identities for tiptop original ingredients

The United States INCI Monograph IDs and Japan JCIA numbers establish clear names and international identities for tiptop’s original ingredient portfolio

INCI MONO ID 39001 · JCIA 22787

Human Endometrial Stem Cell Exosomes

An international ingredient identity spanning the US INCI system and Japan JCIA for a human endometrial stem-cell-derived extracellular-vesicle ingredient

INCI MONO ID 37564 · JCIA 22788

Human Kidney Tubule Epithelial Stem Cell Extract

An international ingredient identity spanning the US INCI system and Japan JCIA for a human kidney tubule epithelial stem-cell-derived ingredient

INCI MONO ID 41692 · JCIA pending

Human Bronchial Epithelial Cell Extracellular Vesicles

The third international INCI identity in tiptop's original ingredient portfolio for a human bronchial epithelial cell extracellular-vesicle ingredient

FDA Orphan Drug Designation

Regend Therapeutics Co., Ltd. · IPF · Designated 2025-02-04 · FDA record 1030224

Public clinical studies

ClinicalTrials.gov

NCT05657184 · NCT06081621 · NCT05638776 · NCT06164093

A 37-publication scientific library

Across 37 research outputs the landscape extends from organ regeneration and stem cells to extracellular vesicles and clinical development Selected publications and primary databases are presented here

p63+Krt5+ distal airway stem cells are essential for lung regeneration

Nature 2015 · DOI 10.1038/nature13903 · PMID 25383540

Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy

Science Translational Medicine 2024 · DOI 10.1126/scitranslmed.adi3360 · PMID 38354225

Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis

Cell Reports Medicine 2024 · DOI 10.1016/j.xcrm.2024.101819 · PMID 39566467

Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis

eLife · DOI 10.7554/eLife.102451.3 · PMID 40036154

Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

Nature Communications 2025 · DOI 10.1038/s41467-025-56501-w · PMID 39900892

Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation

Protein & Cell 2018 · DOI 10.1007/s13238-018-0506-y

Source: FDA ODD FDA Orphan Drug Designation ↗Source: ClinicalTrials.gov NCT05657184 ↗Source: ClinicalTrials.gov NCT06081621 ↗Source: ClinicalTrials.gov NCT05638776 ↗Source: ClinicalTrials.gov NCT06164093 ↗Source: Regend Publications Regend Publications ↗

Academic clinical and regulatory records describe the scientific research context Please refer to each product page for product-specific information and directions

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